The SA Greenberg Lab: The Inclusion Body Myositis Research Project

Research

The goal of our research program is to understand these diseases sufficiently to develop effective therapies. We see and care for patients with inflammatory myopathies and have a research laboratory at Children’s Hospital Boston together with a research program at Brigham and Women’s Hospital. Over 400 patients have enrolled in our research studies to better understand their diseases. We are funded by the National Institutes of Health, the Muscular Dystrophy Association, and the Sporadic Inclusion Body Myositis Research Foundation.

Please see here for our largest programs in inclusion body myositis research and dermatomyositis research

In order to help accelerate the pace of research in inflammatory myopathies, we are making available the Research Plan sections of our NIH funded grants. As of 2009, our NIH funded grants, with the exception of grants containing within them intellectual property that has not yet been protected, will be made publicly available here at the time of receipt of a Notice of Grant Award. We will thus outline what we are best able to do to study these diseases years ahead of eventual publications. This will allow any interested party to see what our funded research plans are and allow capable laboratories to potentially move more quickly than us in areas that they see as promising. We are concerned with maximal speed to progress for patient care, not who publishes first. Knowing that what we write in our NIH grant proposals, if funded, may be publicly available also helps us to make sure that all claims we make in support of obtaining funding are valid and not exaggerated.

Please note that these proposals contain preliminary data and interpretations. Further experiments and analysis don't always confirm these, so that subsequent publications pertaining to them may therefore differ in the data and conclusions drawn. Here are 2 funded NIH grants:

Gene Expression in Inflammatory Myopathies Greenberg R01NS043471-01A1. Funded 01/01/2003 - 12/31/2005

Proteomic Studies in Inclusion Body Myositis Greenberg R21NS057225-01A2. Funded 02/01/2008 - 01/31/2010

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