The SA Greenberg Lab: The Inclusion Body Myositis Research Project

Microarray Technology

Microarray technology allows for the parallel and high-throughput analysis of gene expression present in a biological sample, as reflected in the relative amounts of mRNA transcripts.

The development of this “genomic” technology was fostered by the Human Genome Project (1990-2003), and the explosive growth in available sequence data in databases like GenBank. This data has been used to manufacture microarrays in a process likened to downloading sequence databases onto chips.

A short PowerPoint presentation illustrating the basic principles of microarrays is available for download.

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